• Article  

      Abnormal functional activation and maturation of fronto-striato-temporal and cerebellar regions during sustained attention in autism spectrum disorder 

      Christakou, A.; Giampietro, V.; Brammer, Michael; Smith, A. B.; Robertson, D. M.; Rubia, K.; Bailey, Anthony J.; Baron-Cohen, Simon; Bolton, P. F.; Bullmore, Edward T.; Carrington, S.; Chakrabarti, B.; Daly, Eileen M.; Deoni, Sean C. L.; Ecker, C.; Happé, Francesca; Henty, Julian; Jezzard, Peter; Johnston, Patrick; Jones, D. K.; Lombardo, Michael V.; Madden, A.; Mullins, D.; Murphy, Declan G. M.; Pasco, Greg; Sadek, Susan A.; Spain, D.; Steward, R.; Suckling, John; Wheelwright, Sally J.; Williams, Steven C. R. (2014)
      Objective: Sustained attention problems are common in people with autism spectrum disorder (ASD) and may have significant implications for the diagnosis and management of ASD and associated comorbidities. Furthermore, ASD ...
    • Article  

      Are power calculations useful? A multicentre neuroimaging study 

      Suckling, John; Henty, Julian; Ecker, C.; Deoni, Sean C. L.; Lombardo, Michael V.; Baron-Cohen, Simon; Jezzard, Peter; Barnes, Anna; Chakrabarti, B.; Ooi, Cinly; Lai, Meng-Chuan; Williams, Steven C. R.; Murphy, Declan G. M.; Bullmore, Edward T. (2014)
      There are now many reports of imaging experiments with small cohorts of typical participants that precede large-scale, often multicentre studies of psychiatric and neurological disorders. Data from these calibration ...
    • Article  

      Brain anatomy and its relationship to behavior in adults with autism spectrum disorder: A multicenter magnetic resonance imaging study 

      Ecker,C.; Suckling,John; Deoni,Sean C. L.; Lombardo,Michael V.; Bullmore,Edward T.; Baron-Cohen,Simon; Catani, Marco; Jezzard, Peter; Barnes, Anna; Bailey, Anthony J.; Williams,Steven C. R.; Murphy,Declan G. M. (2012)
      Context: There is consensus that autism spectrum disorder (ASD) is accompanied by differences in neuroanatomy. However, the neural substrates of ASD during adulthood, as well as how these relate to behavioral variation, ...
    • Article  

      Cognition in Males and Females with Autism: Similarities and Differences 

      Lai,Meng-Chuan; Lombardo,Michael V.; Ruigrok,Amber N. V.; Chakrabarti,B.; Wheelwright,Sally J.; Auyeung, Bonnie; Allison, Carrie; Bailey, Anthony J.; Baron-Cohen,Simon; Bolton, P. F.; Bullmore,Edward T.; Carrington, S.; Catani, Marco; Craig, Michael C.; Daly,Eileen M.; Deoni,Sean C. L.; Ecker,C.; Happé,Francesca; Henty, Julian; Jezzard, Peter; Johnston,Patrick; Jones, D. K.; Madden, A.; Mullins, D.; Murphy,Clodagh M.; Murphy,Declan G. M.; Pasco, Greg; Sadek,Susan A.; Spain,D.; Stewart, R.; Suckling,John; Williams,Steven C. R.; Baron-Cohen,Simon (2012)
      The male bias in autism spectrum conditions (ASC) has led to females with ASC being under-researched. This lack of attention to females could hide variability due to sex that may explain some of the heterogeneity within ...
    • Article  

      Decreased centrality of cortical volume covariance networks in autism spectrum disorders 

      Balardin, J. B.; Comfort, W. E.; Daly, Eileen M.; Murphy, Clodagh M.; Andrews, Derek Sayre; Murphy, Declan G. M.; Ecker, C.; Sato, J. R.; Bailey, Anthony J.; Baron-Cohen, Simon; Bolton, P. F.; Bullmore, Edward T.; Carrington, S.; Catani, Marco; Chakrabarti, B.; Craig, Michael C.; Daly, Eileen M.; Deoni, Sean C. L.; Happé, Francesca; Henty, Julian; Jezzard, Peter; Johnston, Patrick; Jones, D. K.; Lai, Meng-Chuan; Lombardo, Michael V.; Madden, A.; Mullins, D.; Murphy, Clodagh M.; Murphy, Declan G. M.; Pasco, Greg; Ruigrok, Amber N. V.; Sadek, Susan A.; Spain, D.; Stewart, R.; Suckling, John; Wheelwright, Sally J.; Williams, Steven C. R.; Wilson, C. E.; MRC AIMS Consortium (2015)
      Autism spectrum disorders (ASD) are a group of neurodevelopmental conditions characterized by atypical structural and functional brain connectivity. Complex network analysis has been mainly used to describe altered ...
    • Article  

      Frontal networks in adults with autism spectrum disorder 

      Catani, Marco; Dell’Acqua, Flavio; Budisavljevic, Sanja; Howells, Henrietta; Schotten, Thiebaut De; Froudist-Walsh, Sean; D'Anna, Lucio; Thompson, A.; Sandrone, Stefano; Bullmore,Edward T.; Suckling,John; Baron-Cohen,Simon; Lombardo,Michael V.; Wheelwright,Sally J.; Chakrabarti,B.; Lai,Meng-Chuan; Ruigrok,Amber N. V.; Leemans, Alexander; Ecker,C.; Craig, Michael C.; Murphy,Declan G. M.; Bailey, Anthony J.; Bolton, P. F.; Carrington, S.; Daly,Eileen M.; Deoni,Sean C. L.; Happé,Francesca; Henty, Julian; Jezzard, Peter; Johnston,Patrick; Jones, D. K.; Madden, A.; Mullins, D.; Murphy,Clodagh M.; Murphy,Declan G. M.; Pasco, Greg; Ruigrok,Amber N. V.; Sadek,Susan A.; Spain,D.; Stewart, R.; Williams,Steven C. R. (2016)
      It has been postulated that autism spectrum disorder is underpinned by an 'atypical connectivity' involving higher-order association brain regions. To test this hypothesis in a large cohort of adults with autism spectrum ...
    • Article  

      Individual differences in brain structure underpin empathizing-systemizing cognitive styles in male adults 

      Lai,Meng-Chuan; Lombardo,Michael V.; Chakrabarti,B.; Ecker,C.; Sadek,Susan A.; Wheelwright,Sally J.; Murphy,Declan G. M.; Suckling,John; Bullmore,Edward T.; Baron-Cohen,Simon; Bailey, Anthony J.; Bolton, P. F.; Carrington, S.; Daly,Eileen M.; Deoni,Sean C. L.; Happé,Francesca; Henty, Julian; Jezzard, Peter; Johnston,Patrick; Jones, D. K.; Madden, A.; Mullins, D.; Murphy,Clodagh M.; Pasco, Greg; Ruigrok,Amber N. V.; Spain,D.; Stewart, R.; Williams,Steven C. R. (2012)
      Individual differences in cognitive style can be characterized along two dimensions: 'systemizing' (S, the drive to analyze or build 'rule-based' systems) and 'empathizing' (E, the drive to identify another's mental state ...
    • Article  

      Obsessive-Compulsive Disorder in Adults with High-Functioning Autism Spectrum Disorder: What Does Self-Report with the OCI-R Tell Us? 

      Cadman, T.; Spain,D.; Johnston,Patrick; Russell, A.; Mataix-Cols, D.; Craig, Michael C.; Deeley, Q.; Robertson, D. M.; Murphy,Clodagh M.; Gillan, N.; Wilson, C. E.; Mendez, M.; Ecker,C.; Daly,Eileen M.; Findon, J.; Glaser, K.; Bailey, Anthony J.; Baron-Cohen,Simon; Bolton, P. F.; Bullmore,Edward T.; Carrington, S.; Chakrabarti,B.; Daly,Eileen M.; Deoni,Sean C. L.; Ecker,C.; Happé,Francesca; Henty, Julian; Jezzard, Peter; Johnston,Patrick; Jones, D. K.; Lombardo,Michael V.; Madden, A.; Mullins, D.; Murphy,Clodagh M.; Murphy,Declan G. M.; Pasco, Greg; Sadek,Susan A.; Spain,D.; Steward, R.; Suckling,John; Wheelwright,Sally J.; Williams,Steven C. R.; Happé,Francesca; Murphy,Clodagh M. (2015)
      Little is known about the symptom profile of obsessive-compulsive disorder (OCD) in individuals who have autism spectrum disorders (ASD). It is also unknown whether self-report questionnaires are useful in measuring OCD ...
    • Article  

      On the brain structure heterogeneity of autism: Parsing out acquisition site effects with significance-weighted principal component analysis 

      Martinez-Murcia, Francisco; Lai,Meng-Chuan; Górriz, Juan Manuel; Ramirez, Javier; Young, Adam M. H.; Deoni,Sean C. L.; Ecker,C.; Lombardo,Michael V.; MRC AIMS Consortium; Baron-Cohen,Simon; Murphy,Declan G. M.; Bullmore,Edward T.; Suckling,John; Bailey, Anthony J.; Baron-Cohen,Simon; Bolton, P. F.; Bullmore,Edward T.; Carrington, S.; Catani, Marco; Chakrabarti,B.; Craig, Michael C.; Daly,Eileen M.; Deoni,Sean C. L.; Ecker,C.; Happé,Francesca; Henty, Julian; Jezzard, Peter; Johnston,Patrick; Jones, D. K.; Lai,Meng-Chuan; Lombardo,Michael V.; Madden, A.; Mullins, D.; Murphy,Clodagh M.; Murphy,Declan G. M.; Pasco, Greg; Ruigrok,Amber N. V.; Sadek,Susan A.; Spain,D.; Stewart, R.; Suckling,John; Wheelwright,Sally J.; Williams,Steven C. R. (2017)
      Neuroimaging studies have reported structural and physiological differences that could help understand the causes and development of Autism Spectrum Disorder (ASD). Many of them rely on multisite designs, with the recruitment ...
    • Article  

      Relationship between surface-based brain morphometric measures and intelligence in autism spectrum disorders: Influence of history of language delay 

      Balardin, J. B.; Sato, J. R.; Vieira, G.; Feng, Yue; Daly,Eileen M.; Murphy,Clodagh M.; Bailey, Anthony J.; Carrington, S.; Jezzard, Peter; Stewart, R.; Baron-Cohen,Simon; Bullmore,Edward T.; Chakrabarti,B.; Henty, Julian; Lai,Meng-Chuan; Lombardo,Michael V.; Pasco, Greg; Ruigrok,Amber N. V.; Sadek,Susan A.; Suckling,John; Wheelwright,Sally J.; Bolton, P. F.; Catani, Marco; Craig, Michael C.; Daly,Eileen M.; Deoni,Sean C. L.; Ecker,C.; Happé,Francesca; Johnston,Patrick; Jones, D. K.; Madden, A.; Mullins, D.; Murphy,Clodagh M.; Murphy,Declan G. M.; Spain,D.; Williams,Steven C. R.; Wilson, C. E.; Murphy,Clodagh M. (2015)
      Autism spectrum disorders (ASD) are a group of conditions that show abnormalities in the neuroanatomy of multiple brain regions. The variability in the development of intelligence and language among individuals on the ...
    • Article  

      Shared neural circuits for mentalizing about the self and others 

      Lombardo, Michael V.; Chakrabarti, B.; Bullmore, Edward T.; Wheelwright, Sally J.; Sadek, Susan A.; Suckling, John; Baron-Cohen, Simon; Bailey, Anthony J.; Bolton, P. F.; Carrington, S.; Daly, Eileen M.; Deoni, Sean C. L.; Ecker, C.; Happé, Francesca; Henty, Julian; Jezzard, Peter; Johnston, Patrick; Jones, D. K.; Madden, A.; Mullins, D.; Murphy, Clodagh M.; Murphy, Declan G. M.; Pasco, Greg; Spain, D.; Stewart, R.; Williams, Steven C. R. (2010)
      Although many examples exist for shared neural representations of self and other, it is unknown how such shared representations interact with the rest of the brain. Furthermore, do high-level inference-based shared mentalizing ...
    • Article  

      White matter microstructural abnormalities in the frontal lobe of adults with antisocial personality disorder 

      Sundram, F.; Deeley, Q.; Sarkar, S.; Daly,Eileen M.; Latham, R.; Craig, Michael C.; Raczek, M.; Fahy, T.; Picchioni, M.; Barker, G. J.; Murphy,Declan G. M.; Bailey, Anthony J.; Baron-Cohen,Simon; Bolton, P. F.; Bullmore,Edward T.; Carrington, S.; Chakrabarti,B.; Daly,Eileen M.; Deoni,Sean C. L.; Ecker,C.; Happé,Francesca; Henty, Julian; Jezzard, Peter; Johnston,Patrick; Jones, D. K.; Lai,Meng-Chuan; Lombardo,Michael V.; Madden, A.; Mullins, D.; Murphy,Clodagh M.; Murphy,Declan G. M.; Pasco, Greg; Sadek,Susan A.; Spain,D.; Steward, R.; Suckling,John; Wheelwright,Sally J.; Williams,Steven C. R. (2012)
      Antisocial personality disorder (ASPD) and psychopathy involve significant interpersonal and behavioural impairments. However, little is known about their underlying neurobiology and in particular, abnormalities in white ...
    • Article  

      White-matter relaxation time and myelin water fraction differences in young adults with autism 

      Deoni,Sean C. L.; Zinkstok, J. R.; Daly,Eileen M.; Ecker,C.; Williams,Steven C. R.; Murphy,Declan G. M.; Bailey, Anthony J.; Baron-Cohen,Simon; Bolton, P. F.; Bullmore,Edward T.; Carrington, S.; Chakrabarti,B.; Daly,Eileen M.; Deoni,Sean C. L.; Ecker,C.; Happé,Francesca; Henty, Julian; Jezzard, Peter; Johnston,Patrick; Jones, D. K.; Lombardo,Michael V.; Madden, A.; Mullins, D.; Murphy,Clodagh M.; Murphy,Declan G. M.; Pasco, Greg; Sadek,Susan A.; Spain,D.; Steward, R.; Suckling,John; Wheelwright,Sally J.; Williams,Steven C. R. (2015)
      Background. Increasing evidence suggests that autism is associated with abnormal white-matter (WM) anatomy and impaired brain 'connectivity'. While myelin plays a critical role in synchronized brain communication, its ...